FlickrSync is a free Windows application that will synchronize the contents of a folder or set of folders on your computer with your Flickr account. It allows the user to define upload settings, create photos sets and define custom filters.
FlickrSync works one-way — photos are synced from your computer to Flickr, but not the other way around. You are able to define Flickr photo permissions, and synchronize according to dates, captions, file names and more. FlickrSync can operate on one specific folder or a set of folders, as well as synchronize all the contents of a folder including sub-folders.
Link via “Flickr File Synchronization Software” by gHacks.net.